Electron Microscopy Facility Policies
Mission and Goal
The facility offers services to investigators both within and outside KUMC on a fee-for-service basis. The EM Facility’s mission is to provide and maintain an infrastructure for state-of-the-art EM services. The Facility’s primary goal is to generate raw EM images and cryo-EM data sets in support of biomedical research at The University of Kansas Medical Center and the surrounding region.
The EM Facility is a cost-recovery service. We work with investigators to find a funding model that works best for each individual lab or center/department. Funding options include:
Model 1: Fee for Service
- The Facility offers fixed-cost options for standard services. These include sample preparation, imaging and analysis. Fees are calculated using institutionally approved formulas based on the actual costs of supplies and labor and are benchmarked to rates at comparable facilities at peer institutions.
Model 2: Research Support on Grants
- EM Facility staff members can be included as personnel on NIH Program Project/Center Grants, Resource Grants, Research Grants, and other comparable sources of external support, and may serve as senior/key personnel (e.g., MPI, co-investigator), Consultant, Collaborator, or Other Significant Contributor (OSC) as appropriate. The precise role is determined by the level of commitment and the nature of the intellectual contributions to the project in areas such as experimental design, data interpretation, authorship, etc.
- Personnel effort committed to a grant will reflect the actual anticipated effort required to meet the demands of the project. The level of effort will be negotiated with the Facility Director and approved by the SOM Office of Research prior to grant submission. This mechanism is not appropriate if effort contribution is estimated to be less than 5% (0.05FTE). The extent of the contributed effort together with the specific tasks to be covered must be submitted to the Core Director prior to grant submission.
- Support of personnel on grants only covers the costs of labor specified in the written agreement. Any additional effort will be billed at fee-for-service rates. Additional charges may include costs of supplies and reagents, equipment access/maintenance fees, and other costs necessary for successful completion of the project.
In cases where Facility personnel contribute substantively to the intellectual development and/or execution of the project, or author any component of the text, authorship should be provided on any resulting manuscript or abstract. Above all, it is important for the Principal Investigator and Facility personnel to agree on criteria for authorship early in their collaboration.
All publications reporting research data generated through the EM facility must cite the Kansas University Medical Center Integrative Imaging Core and reference the core support received from the Kansas Intellectual and Developmental Disability Research Center (NIH U54 HD090216). Where applicable, it is essential that all publications cite NIH Shared Instrumentation S10 awards.
Sample and Data Handling
All SEM and TEM samples, once processed and imaged by the facility are property of the PI and will be returned to the PI or disposed of within 30 days of imaging according to the wishes of the investigator. All imaging files collected on the TEM and SEM should be immediately backed up to the requesting laboratories data repository by the responsible PI lab member. The EM Facility is not liable for the loss of any data due to failure of the facilities’ computer equipment. Data sets generated by the cryo-EM equipment will be held on the KUMC central storage for a duration of 60 days after notification to the investigator of its availability for download. Thereafter, data will be subject to deletion. It is the responsibility of the investigator to ensure that a copy of data is preserved for the future analysis and retained per the appropriate data retention policies.
Terms and Conditions
Client agrees to pay for services in accordance with the terms outlined in written or verbally disseminated quotes including rate schedules, scope of work documents, budgets, and any relevant lab service or other legally binding agreements executed by the client as evidenced by the submission of samples to the Facility. agreement. The EM Facility requires payment arrangements be made before any services are performed, and for payment to be completed upon the release of results. All external clients will be required to adhere to KUMC external customer policies as disseminated at the time of project initiation. In brief, unless otherwise specified, all relevant KUMC external customer identification documents will need to be on file and subsequent service payments are due and payable within thirty (30) days of the date of the invoice.
The EM Facility agrees to perform the services agreed upon in accordance with the highest scientific and professional standards. All parties recognize and understand that the Facility provides services to explore a biological question or scientific hypothesis. The facility makes absolutely no warranties, express or implied, and disclaims all warranties including, but not limited to, implied warranties of merchantability and fitness for a particular purpose. The client's exclusive remedy is, at the KUMC EM Facility’s discretion, a credit for, or re-performance of, the services in question. In no event will the KUMC EM Facility be liable for any consequential, incidental, special or indirect damages, including without limitation, damages for loss of profits, business interruption, loss of business information or property damage sustained by client from the use of, or inability to use, any results, even if the KUMC EM Facility has been advised of the possibility of such damages.
Both parties each agree to maintain in confidence and not disclose to third parties any confidential information that is disclosed to one by the other party. This includes pricing information and all communications.
Intellectual Property and Use of Data
Following settlement of all invoices, all compilations of scientific and technical data produced or prepared by the KUMC EM Facility in the performance of services requested shall be the exclusive property of the client and shall be deemed to be works made for hire. Any work resulting from unpaid services and all associated intellectual property shall remain the exclusive property of the KUMC EM Facility. By using the facility, unless otherwise specified and agreed upon by both parties, the client gives permission to the KUMC EM Facility to utilize his/her data for internal development of core services, after services are complete and deliverables are met. These provisions shall survive any termination or expiration of this Agreement.